This study investigated the relationship between job enrichment and job performance of employees in the manufacturing industry, using Niger Mills Industries Limited located Calabar, Cross River State, Nigeria. The study further aims at ascertaining the extent to which jobs redesign can possibly not only enhance employee performance but also employee job satisfaction. The entire staff strength of 240 permanent employee of Niger Mills Industries Ltd, constituted the population of this study, from which a sample of 150 was carried out with the aid of the Tara Yamani’s formula. Questionnaire was administered on the 150 respondents and data collected was analyzed and hypothesized at 0.05 level of significance. Findings from data analysis showed that management of Niger Mill industry infrequently re-design jobs, which would have allowed the introduction of new and more challenging job responsibilities. It was also revealed that the management of Niger Mills Industries do not appropriately expose and involve the employees in decisions making and accountability to work outcomes. This study therefore recommended that Niger Mills Industry Limited need to conduct job re-design to correct the dysfunctional aspect of precious work design. It was also particularly recommended that employees should be given new and more challenging jobs as well as be given opportunities for greater accountability to personal work outcomes.